Global Congress on Infectious Diseases & HIV/AIDS
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Accepted Abstracts

Effectiveness of early initiation of antiretroviral therapy in adults with HIV associated tuberculosis in Lesotho in 2012

Maletsatsi Lenela*
University of KwaZulu-Natal, South Africa

Citation: Lenela M (2020) Effectiveness of early initiation of antiretroviral therapy in adults with HIV associated tuberculosis in Lesotho in 2012. SciTech Infectious Diseases 2020. Mauritius

Received: August 21, 2019         Accepted: August 27, 2019         Published: August 27, 2019

Abstract

Background: Lesotho has a huge burden of human immunodeficiency virus associated tuberculosis (HIV-TB). In this study we compared the effectiveness of early versus late commencement of antiretroviral therapy (ART) in adults living with HIV-TB in Lesotho.

Methods: Three out of 17 hospitals were randomly selected and data extracted from the hospitals’ tuberculosis (TB) treatment registers for 247 adults living with HIV-TB who completed TB therapy during the first quarter of 2012.

Results: Eighty (32%) commenced ART early (p < 0.001).

Conclusions: Effective treatment exists for managing HIV-TB simultaneously. The guidelines for initiation of ART in adult HIV-TB in Lesotho have not been fully implemented, but those who commenced ART had significant clinical benefits. Health departments must address the challenges encountered in treating HIV-TB simultaneously to ensure those co-infected receive optimal care.