Introduction-objective: In general, toxoplasmosis does not have serious consequences, but its occurrence during pregnancy exposes to the risk of congenital toxoplasmosis. This brings into play the fetal and neonatal prognosis. The main objective of this study is to establish the incidence of toxoplasma seroconversion during pregnancy.

Materials and methods: This is a descriptive cross-sectional study conducted at the maternity hospital of the city of Batna among pregnant women at term of their pregnancies. This study was carried out over a period of three months from December 2022 to February 2023. All pregnant women had toxoplasma serology (IgM and IgG).

Results: During the study period we recruited 511 pregnant women whose average age of women is 29 years, with extremes ranging from 18 to 47 years. the majority of women are multiparous (65.9%). Toxoplasmosis serology was performed systematically in most pregnant women during the first trimester, ie 68.2% of them. While only 1.5% did so during their last trimester of pregnancy. Of all the toxoplasma serologies that were performed, 54.6% of pregnant women had negative serology. On the other hand, 45.4% of the serologies were positive. Among all HIV-negative pregnant women, only 2 (0.72%) women had a seroconversion.

Conclusion: Prevention of congenital toxoplasmosis is based on screening, awareness of potential risks and education, as well as regular monitoring of antibody levels in women who have not been infected with toxoplasmosis.

Keywords: Congenital toxoplasmosis, Pregnant women, Serology, Seroconversion