45th Global Congress on Infectious Diseases: Research on Diagnosis and Therapeutics
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Accepted Abstracts

A Multidrug- Resistance Pattern of an Escherichia coli Strain Isolated from Diarrheal Stools at the China-Guinea Friendship Hospital of Kipe in Conakry

Abdoulaye Makanera 1, 2, *, Mariam Conde 1, Taliby Dos Camara 3, Mamadou Alpha Diallo 1, Mariama Conde 1, Daouda Camara1, Alpha Oumar Barry1, Tiguidanke Diakite1 and Oumar Souare 1 et al

1Biomedical Laboratory of the China-Guinea Friendship Hospital, Kipe, Cite des Médecins, Republic of Guinea.
2Department of Medicine, Faculty of Health Sciences and Techniques, Chair of Fundamental Sciences, Gamal Abdel Nasser University of Conakry, Republic of Guinea.
3Microbiology Laboratory, Department of Biology, Faculty of Sciences, and Gamal Abdel Nasser University of Conakry, Republic of Guinea.

Citation: Makanera A, Conde M, Camara TD, Diallo  MA, Conde M et al (2023) A Multidrug- Resistance Pattern of an Escherichia coli Strain Isolated from Diarrheal Stools at the China-Guinea Friendship Hospital of Kipe in Conakry. SciTech Infectious Diseases 2023.

Received: November 23, 2023         Accepted: November 23, 2023         Published: November 23, 2023

Abstract

Introduction: Diarrheal infections associated to multidrug resistant bacteria are a public health problem, particularly in the tropics.
Objective: The aim of this study was to describe a Multidrug resistant strain of Escherichia coli (E. coli) isolated from diarrheal stools.
Patients and Methods: A sample of diarrheal stools from a 30 years old housekeeper patient was analysed at ChinaGuinea Friendship Hospital of Kipé/Conakry. Parasitological examination by optical microscopy, followed by bacteriological analysis were done. Cultures were carried out on different agar media. Bacterial identification, antibiograms and minimum inhibitory concentrations (MIC) were performed using the Vitek 2 System.
Results: The isolated E. coli strain was sensitive only to 4 of 29 antibiotics tested including imipenem, ertapenem, amikacin and nitrofurantoin. Intermediate sensitivity was detected towards minocycline. In contrast, this strain was resistant to piperacillin, cefuroxime, cefuroxime axetil, cefixime, ceftriaxone, cefepime, aztreonam, meropenem, levofloxacin, ofloxacin, tetracycline, tigecycline, chloramphenicol, trimethoprim, ampicillin, amoxicillin/clavulanic acid, ticarcillin, piperacillin/tazobactam, cephalothin, cefotaxime, ceftazidime, gentamicin, tobramycin, nalidixic acid, ciprofloxacin, ofloxacin and trimethoprim/sulfamethoxazole with high MICs.
Conclusion:The treatment of this multidrug-resistant Escherichia coli diarrheal infection requires appropriate antibiotic therapy, based on the results of an accurate antibiogram to be performed with rapid means for better patient care.
Keywords: Escherichia coli, Diarrheal stools, Multidrug-resistance, Antibiotics, Kipe/Conakry

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