Severe Sepsis with Kidney and Liver Dysfunction in a Sickle Cell Patient at Brazzaville: About Three Cases
Talomg Tamekué SL1*, Kocko I 1,2, Galiba AtipoTsiba FO1,2,3, Ngolet Ocini L1,2,3, Simo Louokdom J1, Tchidjo Ngamo L1 and Elira Dokekias1,2,3
1Faculte des Sciences de la Santé, Université Marien Ngouabi , Brazzaville (Congo)
2Service d’Hématologie Clinique, CHU de Brazzaville (Congo)
3Centre National de Référence de la Drépanocytose (CNRD), Brazzaville (Congo)
Citation: Talomg Tamekue SL*, Kocko I, Galiba AtipoTsiba FO, Ngolet Ocini L, Simo Louokdom J et al (2021) Severe Sepsis with Kidney and Liver Dysfunction in a Sickle Cell Patient at Brazzaville: About Three Cases. SciTech Immuno-Microbiology 2021.
Received: August 20, 2021 Accepted: August 21, 2021 Published: August 21, 2021
Abstract
Introduction: Sickle cell anemia, in its evolution there is an infectious risk both in children and adults. Infectious complications are the main cause of morbidity and mortality in children with sickle cell disease.
Patients and case report: We report three cases of severe sepsis with renal and hepatic dysfunction during homozygous sickle cell disease, recorded in the Clinical Haematology Department of the Brazzaville teaching Hospital. The patients were female, aged 10, 17 and 20 years respectively, and were not followed up. The 20-years-old patient was 20-weeks and 5 days pregnant. On hydration, blood transfusion and antibiotic therapy, the outcome was favorable in all patients.
Conclusion: regular follow-up, antibiotic prophylaxis and adequate vaccination of sickle cell patients are necessary to prevent sepsis and its complications.
Keywords: Homozygous sickle cell disease, Severe sepsis, Kidney and liver dysfunction, Brazzaville
