Global Summit on Biomedical & Cancer Research
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Accepted Abstracts

Changes in Spirometry Indices and Lung Cancer Mortality Risk Estimation in Concrete Workers Exposed to Crystalline Silica

Somayeh Rahimi Moghadam1, Narges Khanjani2, Mahmoud Mohamadyan3, Mojtaba Emkani4* and Mohamad Naser Layegh Tizabi5

1,5 Department of Occupational Health Engineering, Neyshabur University of Medical Sciences, Neyshabur, Iran
Environmental Health Engineering Research Center, Kerman University of Medical Sciences, Kerman, Iran
Department of Occupational Health Engineering, school of Health, Mazandaran University of Medical Sciences, Sari, Iran
Shiraz University of Medical Sciences, Shiraz, Iran.

Moghadam SR, Khanjani N, Mohamadyan M, Emkani M, Tizabi MNL (2022) Changes in Spirometry Indices and Lung Cancer Mortality Risk Estimation in Concrete Workers Exposed to Crystalline Silica. SciTech Biomed-Cancer 2022.

Received: May 04, 2022         Accepted: May 09, 2022         Published: May 09, 2022


The health of workers in the concrete and cement industries can be at risk due to occupational exposure to silica dust. The purpose of this study was to evaluate the changes of pulmonary parameters and risk of mortality from lung cancer in concrete workers exposed to crystalline silica.
This cross-sectional study was performed on 72 male workers exposed to silica at a concrete manufacturing plant in Neyshabur, Iran. Respiratory zone air sampling was performed using the standard NIOSH7601 method using individual sampling pumps and membrane filters. Then, the amount of silica in the samples was determined using the Fourier Transform Infraredtechnique. The risk of death from lung cancer was determined using Rice et al.’s model. Respiratory indices were measured using a spirometer. Data were analyzed by the SPSS 20 software. Occupational exposure to silica was 0.025 mg/m3 and mortality was estimated to be 7-94 per thousand. All spirometry indices significantly decreased during these 4 years of exposure to silica dust. The respiratory pattern of 22% of the exposed workers was obstructiveand this prevalence was significantly higher than the control group.
The results showed that although the average occupational exposure to silica in these concrete workers was below the recommended threshold of national and international organizations, their risk of death was significantly higher; and workers' lung indices had significantly decreased over four years. Therefore, appropriate measures should be taken to reduce silica exposure among these workers.
Keywords: Concrete, Pulmonary function, Lung cancer, Risk, Silica dust