In order to restore the cardiac damaged tissues cardiac patches have been employed Elecgtrospinning technique has been adopted to design cardiac patch and the same has been assessed with regard to its physicochemical characteristics. Polyurethane coated with cobalt nano particles has been used to prepare the patch and has been synthesized using green approach by means of green tea containing polyphenols. Nanoparticles with varied morphology have been obtained using different concentrations of cobalt salt concentrations mixed with green tea solution. Also, cobalt nanoparticles so synthesized CoNPs with with specified concentration has been applied on the polyurethane adopting electrospinning technique. Studies using SEM have revealed that the developed patches having greater concentration of cobalt nano particles showed smaller diameter in comparison with polyurethane. The polyurethane cobalt nanoparticles patch rendered hydrophilic surface with lower ratio of cobalt nano particles. Whereas,greater ratio of cobalt nano particles have shown improved strength compared to the pristine polyurethae. Patches with the improved physicochemical properties and mechanical strength can be exploited for cardiac applications.
Keywords: Cardiac patches, Electrospinning, Cobalt nanoparticles, Green tea, Nanocomposite