13th International Conference on Biomedical and Cancer Research (Part II)
  • Follow

Accepted Abstracts

Methylation of Nucleic Acids as a Means of Increasing Their Informational Activity

Gennadiy Vladimirovich Zhizhin*
Russian Academy of Natural Sciences, Russian Federation

Citation: Zhizhin GV (2021) Methylation of Nucleic Acids as a Means of Increasing Their Informational Activity. SciTech Biomed-Cancer Sciences 2021. 
 

Received: December 17, 2020         Accepted: December 21, 2020         Published: December 21, 2020

Abstract

Impact investigated of nucleic acid methylation on the geometric characteristics of nucleic acids. Such methylation is characteristic of viral nucleic acids when infected with viruses of organisms. It was shown that methylation of nitrogenous bases leads to an increase in their dimension, creating a higher dimension of the bases. This, in accordance with the recently established law for the conservation of incidents (Zhizhin), sharply increases the intensity of information transfer between elements of different dimension of nucleic acids. At the same time, the intensity of transmission of hereditary information in the polytopic of hereditary information increases significantly. It has been established that the intensity of information transfer in the methylated polytope of hereditary information increases by more than 2000 times in comparison with the unmethylated polytope of hereditary information. It should be assumed that it is this property that activates viral nucleic acids when they infect organisms, weakening organisms, including due to the use of methyl groups of organism cells by viruses. To counteract this activation of viral nucleic acids it is necessary to increase the concentration of methyl groups in the nitrogenous bases of the nucleic acids of the organism. This will enhance the transfer of information in the nucleic acids of the organism, activating them in the process of confrontation with the nucleic acids of viruses. It should be emphasized that the dimension of the methylated polytope of hereditary information is 18, on 5 units higher than the dimension of unmethylated polytope of hereditary information. This indicates that the interaction of nucleic acids during infection of the organism with viruses occurs in space of a very high dimension.
 
Keywords: Dimension, Polytope, Space, Molecule, Incidence, Nucleic acid, Information