Khalid Aftab1*, Sidrah Khan2
1. Sialkot Medical College, Pakistan
2. Liaquat National Hospital Medical College, Pakistan
Citation: Aftab K, Khan S (2019) Bio-Similar of Ciprofloxacin 500mg. SciTech Biomed-Cancer Sciences 2019. Tokyo: Japan
Received: April 23, 2019 Accepted: April 25, 2019 Published: April 26, 2019
The Pharmacokinetic and bio-availabilities of two brands of Ciprofloxacin - 500 mg tablets, from local and multinational firms were studied in fourteen healthy human (male) volunteers after oral administration (as single dose) by double blind cross-over design. The absorptions were rapid and excellent. The bio-availabilities of Ciprofloxacin were determined from area under the curve of plasma concentration versus time. We did not find any significant differences in their bio-availabiities and propose that they should be clinically equally effective & Bio-Similar.