Cancer is one of the biggest challenges in the medical world that has affected many people since the past. The efforts of researchers in other scientific fields have also been aimed at reducing the complications caused by this disease, and as a researcher and professor in this field, we decided to present this issue in this conference.

Today, cancer is one of the main causes of death among humans. Therefore, it is very important to find effective treatment methods. As you know; Chemotherapy is the most common way to treat cancer. However, it should not be forgotten that the direct use of anticancer drugs is associated with many unwanted side effects. For this reason, in recent decades, there have been many studies in the field of designing new drug delivery systems, especially using nanoparticles.

In recent years, new drug carrier systems, especially carriers based on porous nanoparticles with high loading capacity and controlled drug release capability, have largely overcome the problems and limitations. Covalent organic frameworks are the most remarkable emerging porous organic materials due to their unique properties. Therefore, in this research plan, covalent organic frameworks with immune bonds obtained as a result of the reaction of different aldehydes and amines on a substrate of nanoparticles or polysaccharides were used, which can be used for targeted drug delivery to cancer cells.

Today, researchers in the field of nanomedicine also investigate and study the effect of the use of nanomaterials on the treatment of diseases in the field of biomedicine, and the published results show that generally nanomaterials are able to provide more effective approaches in disease diagnosis and drug delivery.

So far, several studies have been conducted to investigate the capability of nanocomposite systems in cancer drug delivery. However, our search in these sources showed that so far there is no research on the design, synthesis and performance evaluation of the nano systems presented in this research, for the controlled delivery and release of chemotherapy drugs to breast cancer cells.