Liquid smoke from Tali bamboo (Gigantochloaapus) is thought to have the potential to help the wound healing process in mice. This study aimed to determine the compounds and potential of liquid smoke in wound healing. This research was an experimental research using posttest only control group design. A total of 5 male mice were each used for treatment at each administration of liquid smoke with groups of liquid smoke concentrations of 100%, 50%, 25%, positive control and negative control. The method used was the liquid chromatography–mass spectrometry technique and the results were analyzed with a mass bank database to see the compounds contained in liquid smoke. In vivo tests were carried out to observe the diameter and percentage of wound healing in mice that occurred for 14 days. Data were analyzed using the Kruskal Wallis test and Spearman correlation. The results showed that liquid smoke contains alkaloids and flavonoids compounds that have antibacterial, anti-inflammatory properties that can prevent inflammation and can heal wounds. Statistically, there was a difference in the average diameter of the percentage of wound healing with other treatments (p = 0.020) and there was an effect between the administration of graded doses and the percentage of wound healing in mice (p = 0.029). Conclusions, liquid smoke with a concentration of 100% is able to help and accelerate the wound healing process compared to other treatments.
Keywords: Liquid smoke, Gigantochloaapus, Bamboo, Wounds