Drug Use Analysis (DUR) or Drug Use Assessment (DUE) is known as an important quality management method for evaluating and improving substance use and patient care. It is an ongoing, systematic method to examine the pattern of drug administration in a number of clinical environments, with recommendations or defined criteria to facilitate the acceptable and efficient use of drugs. The DUE can be organised for evaluation and to improve the method of prescribing or dispensing the medication according to acceptable indications, dosage, drug reactions, therapeutic efficacy and cost-effectiveness.
Aim: To evaluate the drug utilisation pattern of cephalosporins.
Methodology: A retrospective observational study was performed for a period of 2 months among the hospitalised patients who received cephalosporins for different indications in which 100 patients were enrolled

Result: Inappropriate use of drug therapy has been found in phase 1 (pre- intervention) and interventions have been conducted to rationalise the appropriate use of drugs in terms of indication, dose, dose length, individualised dosage modification, which has been strengthened in phase 2 by providing effective guidance on the application of DUE and interventions.

Keywords: Drug Utilization Review, Drug use Eevaluation, Rational use of drug, Intervention