Non-communicable diseases (NCDs) are globally health issues as they cause deaths of approximately 60% worldwide. In Rwanda, at every levels of health-care delivery, there is no enough data for kidney diseases and other  NCDs management. To maintain survival of end stage renal disease (ESRD) patients, treatment known as renal replacement therapy (RRT) appears to be the best option. RRT will eventually be established in Rwanda. The prime objective of this study was to assess blood urea nitrogen (BUN) and serum creatinine levels on graft survivals following kidney transplantation at King Faisal hospital of Kigali. This was a retrospective study. Laboratory and medical records were used to obtain patient data. Statistical package for the social sciences (SPSS) was utilized in analysis of data. Normal BUN and serum creatinine levels varied between 77.4 - 93.5 and 67.7 - 87.1%, respectively. Abnormal high levels of BUN were 3.2 - 19.4% while high creatinine varied between and 6.5 - 29.0%. Abnormal low levels of BUN and creatinine ranged between 0.0 - 6.5 and 3.2 - 9.7%, respectively. 19.35% of the study population had diabetes mellitus, 35.48% suffering from hypertension, and 6.45% were with antibody mediated rejection. Diabetes, hypertension and antibody mediated were statistically significant. Therefore, the follow up of biochemical tests happening during the 1^st  year renal transplant  are very important for  raising up a durable health on graft survival. Subgroups of transplants with noticeably decreased implant half-life can be recognized. The government, nephrologists, and health care nurses have to provide equipments, knowledge and intensive cares to transplants and encourage them for doing follow up every month to avoid graft failure.

Keywords:Renal transplantation, Blood urea nitrogen, Serum creatinine, King Faisal Hospital