17th International Conference on Neurology and Spine Disorders
  • Follow

Accepted Abstracts

Postoperative Pain Management in Lower Limb Surgery Patients Using Transdermal Buprenorphine and Diclofenac Formulation

Jobin John*, Chrismol Devassy and Reshma Avicot Renny
National College of Pharmacy, India

Citation: John J, Devassy C, Renny RA (2021) Postoperative Pain Management in Lower Limb Surgery Patients Using Transdermal Buprenorphine and Diclofenac Formulation. SciTech Central Neurology 2021. 

Received: January 13, 2021         Accepted: January 16, 2021         Published: January 16, 2021

Abstract

Background: The present study was carried out to determine the difference in the effectiveness of buprenorphine and diclofenac transdermal patches in attenuating postoperative pain, following lower limb orthopedic surgeries in a tertiary care teaching hospital in Kerala, South India.
 
Methods: 88 patients who underwent lower limb orthopedic surgeries under spinal anesthesia were included in this randomized single-blind study. Group A received transdermal Buprenorphine 10mcg/h patch and Group B received transdermal Diclofenac 200mg patch. Both patches were, applied 30 minutes before spinal anesthesia and the intensity of pain was determined using, visual analog scale (VAS) and faces pain scale (FPS-R). The pain scores at every 4th hour for 24 hours were measured and recorded for all patients. Side-effects and patient satisfaction were checked and evaluated.
 
Results: 39 patients (44.31%) out of a total of 88 patients required rescue analgesia. Mean and maximum VAS and FPS scores of patients in the Diclofenac group was higher. Adverse effect: Buprenorphine group complained of nausea (22.7%), headache (15.9%), and dizziness (13.6%) while the Diclofenac group complained of nausea (18.2%). Majority of patients in both groups expressed their satisfaction with transdermal patch therapy as GOOD (93.18%).
 
Conclusion: Transdermal Buprenorphine patch was more effective in attenuating postoperative pain than transdermal Diclofenac patch, following lower limb orthopedic surgeries.
 
Keywords: Postoperative pain, Lower limb orthopedic surgery, Transdermal buprenorphine, Transdermal diclofenac, Visual analog scale, Faces pain scale

Supporters