9th International Congress on Biotechnology and Food Sciences
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Accepted Abstracts

Investigation of Heavy Metals Composition in Selected Abakaliki Herbal Preparations and Modern Medicines for Management of Disease Conditions in Abakaliki Ebonyi State Nigeria

Ali Fredrick Ugadu1*, OF Orinya1, MC Ominyi1, LN Ebenyi1, RC Ogbuatu1, ME Ogbanshi1, SC Onuoha1, FN Nwalo2, CA Nsud3, Onu Euslar N4

1 Ebonyi State University, Nigeria
2 Alex Ekwueme Federal University, Nigeria
3 Enugu State University of Science and Technology, Nigeria
4 Health Technology, Nigeria 

Citation: Ugadu AF, Orinya OF, Ominyi MC, Ebenyi LN, Ogbuatu RC et al (2020) Investigation of Heavy Metals Composition in Selected Abakaliki Herbal Preparations and Modern Medicines for Management of Disease Conditions in Abakaliki Ebonyi State Nigeria. SciTech BioTech-Food Sciences 2020. Thailand 

 

Received: November 30, 2019         Accepted: December 11, 2019         Published: December 11, 2019

Abstract

The  use of herbal medicines for treatment of different disease conditions has been is as old as human existence .These herbal products / synthetic drugs contain chemical substances  which are  considered  as beneficial while others  were not. Herbal products and synthetic drugs are consumed extensively in Ebonyi State for their  medicinal properties. This study was undertaken  to evaluate  the concentration of heavy metals in selected traditional  herbal preparation and synthetic drugs consumed in Abakaliki  Ebonyi State. A total of 11 samples  were used for  the study : seven herbal preparations and 4 synthetic drugs . They include: Healing bitters, orak herbal formula, Goko cleanser,Clara ULC, pro-life herbal remedy, golden seed ,  Deep root herbal mixtures, relcer gel, Reprofen suspension, ampiclox, and P-alaxin, . The drugs and herbal mixtures were purchased from the local Abakpa market in Abakaliki Ebonyi State Nigeria .They were  analyzed for their, lead, copper, iron, manganese, potassium, chromium, Nikel , zinc calcium, mercury  ,manganese, contents. Microwave-assisted digestion were used for the dissolution of the samples and heavy metals concentration was determined using Atomic Absorption Spectrometry (AAS). Metals were found to be present in varied concentrations in the herb and synthetic drug samples. The concentration ranges were found as follows: 0.03-12.35 µg/g for essential metals and 0.12-3 µg/g for toxic metals respectively for both herbal preparation and synthetic drugs .The gross level of contamination of lead, mercury,  and chromium  metals could be attributed to poor adherence to good manufacturing practice and effective surveillance . Hence, this work suggest immediate action  by relevant authorities  in order to avert impeding  health  hazards from  gradual accumulation of these  toxic metals in the body  system of consumers of  these  herbal preparations and modern drugs , to ensure safety of these medicines in Ebonyi State  Nigeria.
Key words :Drugs, heavy metals, disease, herb, and hazards.