Pharmacology & Drug Development Congress
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Accepted Abstracts

Drug Development on Chemical Therapeutics/Antidote for Chemical Weapons known as SodaSulphanecobalamin

Salako N Olatuniji*
Center for Countermeasures against Chemical and Biological Warfare Agents, Lagos

Citation: Olatunji SN (2020) Drug Development on Chemical Therapeutics/Antidote for Chemical Weapons known as SodaSulphanecobalamin. SciTech Central Pharma 2020. Mauritius 

Received: October 24, 2019         Accepted: November 01, 2019         Published: November 04, 2019

Abstract

SodaSulphanecobalamin (Na4S5CoC69N15H 89O26) is an antidote for Chemical weapons, which detoxify and decentralized the toxic substances in any chemical based threat mainly, classical chemical agent threat categories include vesicant or blister agents (e.g., sulfur mustard), blood agents (e.g., cyanide), respiratory agents (e.g., phosgene), and nerve agents (e.g., GA or Tabun, GB or Sarin, GD or Soman, and VX) as well as lung damaging agents (Chlorine, diphosgene). It dissociate the toxic components in each chemical weapons, either nerves agent, blister agent or mustard gas to a nontoxic substance when administered and doesn't have any adverse effects unlike Atropine (which has little effect on nicotinic effect, such as muscle twitching, flaccidity) and other antidotes been tested for neutralizing or countermeasures for a particular chemical based threat. It displaces the Cyanides to a free toxic compound, thiocyanocobalamin .It removes the burns when the sulfur mustard is been contacted through skin, and eye The antidote (SodaSulphanecobalamin) which is sulfur drug group (H-S) bends the mustard makes the anditodal removes mustard from the body, of which can be used as treatment for Organic Arsenical. It also added the amide group of protein when used. However, recent studies shows that this antidote can serve as a replacement for the antidote of Orange agent (2, 3, 4, 7-tetra chlorobenzodioxin) which displaced millions of Vietnam Citizens during the World War II and displaces chlorobenzo to sodium benzoate and saline. Though Mercury (I) Oxalate is been used for this antidote for the orange agent, but we all know that Mercury is highly toxic and poisonous to the human .Nerve agents developed in the 1930s and 1940s were stockpiled during the Cold War. More recently, nerve agents have been used in the Iran–Iraq War in the 1980s, the Japanese terrorist attacks by the Aum Shinrikyo cult in 1995 and attacks in Syria in 2017. Recently, the Salisbury Nerve attack on March 4 th 2018, when SodaSulphanecobalamin is been used for nerves agent antidotal , it dissociates organophosphate to phosphoric acid which helps in metabolism of the body.