TB is one of the most infectious diseases. Now with the diseases like Acquired immuno deficient Syndrome (AIDS) and Diabetes the disease is able to get a foothold in developed countries as well. Various TB control efforts have been started, but the emergence of drug resistant (DR) strains have created an unwanted pressure on such programs. It is still true to a large extent today Tuberculosis (TB) is an airborne infectious disease caused by organisms of the Mycobacterium Tuberculosis complex. Mycobacterium Tuberculosis complex includes M. africanum, M. microti, Mtb, and M. bovis. M. tuberculosis can cause disease in lungs and any part of the body. Called Extrapulmonary tuberculosis (EPTB) describes the various conditions caused by Mycobacterium tuberculosis infection of organs or tissues outside the lungs lymph. Node, pleural, renal/urinary tract, tuberculous meningitis, bone joint.

Mtb is a microscopic, slow growing, rod shaped bacterium that is transmitted through the air when the infected person coughs spits or sneezes. Acid Fast bacterium that can remain in dried aerosol droplets. TB is a disease that   spreads through the air from one person to another. Like Cough, laughing, sneezing or singing releases more bacteria than breathing. The single - celled bacilli primarily attacks the lungs. TB is spread to easily others. TB spreads when a person who has active disease exhales air that contains. These bacteria can float in the air for several hours. The specific symptoms will depend on whether the infection is in the lungs or in another part of the body (EPTB). People with active TB disease can spread the bacteria to others, feel sick, and can have symptoms including fever, night sweats, cough, and weight loss.TB and AIDS is double edged weapon. TB is the most common infection in people living with HIV virus.

TB vaccines - Success story started with discovery of tubercle bacillus in 1892 by Robert Koch, followed by development of BCG vaccine for prevention in 1922. The current Bacilli Calmette Guerin (BCG) vaccine Efforts for TB control. Honorable Prime Minister launched a campaign to eradicate TB from India by 2025