Received: November 17, 2018 Accepted: November 21, 2018 Published: November 26, 2018
Due to being partially attributable to the varying effects of climate change, spatio-temporal scale, and different types of host-pathogen systems, the debate on the potential human health impacts remains polarizing, in spite of a growing progress in determining climate change effects on human infectious diseases. While regions geographically experiencing higher temperature anomalies have been provided more study attention, the Earth’ s most vulnerable regions to climate variability and extreme events unfortunately have been less studied. Agreements on the response of human infectious diseases to climate change tend to converge from local to global scales. Then the number of mechanistic studies are slowly growing, with abundance of findings of rapidly growing of statistical methods, for examples, using seasonal auto-regressive integrated moving average model with local weather conditions in forecasting hand-foot-mouth disease, using generalized estimating equation models/multivariate random-effects meta-regression analyses in quantifying the city-specific climate change-malaria associations, etc. There are negative or uncertain reports on responses of human infectious diseases to climate change has been increasing. Research gaps and trends should be addressed in the near future, including impact of climate change on respiratory infectious diseases and human infectious diseases other than vector-borne diseases.