The study is aimed at the possible certification of arecant extracts efficacy as therapeutic agent against SARS corona virus.Then we could convert their use to a therapeutic use against several respiratory viral germ. It may become prophylactic and/or therapeutic regime for virus infection. Since Corona virus cannot be cultured , we have to resort to straight studies on influenza virus .Both viruses share similar structural properties and symptoms in infection. First based on antimicrobial potential and antioxidant activity of the efficacy of arecanut extract(AE) proved that studies could be done to compare the effect of extract against influenza virus and corona virus. This AEt has a potential antifungal activity against unicellular yeast Candida albicans  and mycelia fungi Mucor sp and Aspergillus flavus. In the tube method against bacteria and Candida sp , the test samples Absorbance was read at 530 nm at different time intervals. Disc Diffusion Method was used to evaluate the Zone of clearance suggestive of the zone of inhibition of the AE against fungi by taking Nystatin as standard.  Inhibition of Aflatoxin production was checked by Pons Method. 85 % inhibition of the production of aflatoxin by Aspergillus flavus was  at,between 100-250 µg/ml of the AE. The AE was shown to inhibit the viral growth and propogation of AVIAN  viruses  NDV(New castle Disease Virus) and Egg Drop Syndrome Virus( EDS ) in embryonated culture. Invitro antioxidant studies showed that AE could inhibit superoxide radical production, could inhibit hydroxyl radicals and could prevent lipid peroxidation.  AE  could scavenge DPPH (DI PHENYL-2-PICRYL Hydrazyl ) radicals and also ABTS(Di ammonium salt)(2,2’-azinobis-(3-ethylbenzthiazoline-6-sulphonic acid). In FRAP(Ferric Reducing Antioxidant Power) assay, the reduction of ferric to ferrous is also seen in a concentration dependant manner. Concentration ranging from 5µg/ml – 100 µg/ml showed the potential  of AE  to scavenge 50% free radicals.  Cytotoxicity studies of AE against Influenza virus previously reported and  documented with scientific evidence proved all the more its efficacy in the development of new antiviral agent.
Result: The present line of thinking was supported by results to show the effectiveness of AQUEOUS AE as potential therapeutic agent against Influenza virus. Thus probably its use against Corona virus  be established with further scientific evidence is the perception. This is based on AE antimicrobial, antioxidant activity. Further, the identification and purification of their effective components  leads to the use of AE  as traditional cure.
Keywords: Arecanut, Antimicrobial, Antioxidant, Antiviral