39th World Seminar on Pharmacology & Drug Development
  • Follow

Accepted Abstracts

Evaluation of the Effect of Corticosteroid Injection on Supratip SkinThickness in Rhinoplasty Surgery

Mahmood Ghahghai*1, Abdolreza Rouientan Sahar2, Sotoodeh Ghorbani3

1Department of Plastic and Reconstructive Surgery, Taleghani EducationalHospital, Jundishapur University of Medical Sciences, Ahvaz, Iran.
2Department of Plastic and Reconstructive Surgery, Khordad EducationalHospital, Shahid Beheshti University of Medical SciencesTehran, Iran
3Department of Epidemiology School of Public health and Safety, Shahid BeheshtiUniversity of Medical Sciences, Tehran, Iran

Citation:
 Ghahghai M, Sahar AR,  Ghorbani S (2023) Evaluation of the Effect of Corticosteroid Injection on Supratip SkinThickness in Rhinoplasty Surgery. SciTech Central Pharma 2023.

 

Received: April 03, 2023         Accepted: April 05, 2023         Published: April 05, 2023

Abstract

Introduction: Thick, sebaceous gland-rich skin and subcutaneous tissue are themost unsuitable types of skin to achieve the desired outcome of a rhinoplastyoperation. Corticosteroid injection is a treatment that can prevent this condition.The present study aimed to investigate the effect of intraoperative and first-weekpost-operative triamcinolone injection on reducing skin thickness in patients withthick skin following a rhinoplasty operation.
Method: A randomized clinical trial with a parallel design was performed onpatients referred for rhinoplasty with a supratip thickness of over 3.1 mm. Thepatients were divided into three groups of 20 individuals. The third group did notundergo triamcinolone injection during the rhinoplasty operation. At the end ofthe study, supratip skin thickness was measured as the trial outcome in thesecond, fourth, and sixteenth postoperative weeks using sonography.
Results: 60 patients underwent rhinoplasty (in three groups of 20 individuals).The mean age of the participants was 24.9 ± 7.8 years, of which 42 (70%) werefemale and 18 (30%) were male. The supratip skin thickness was significantlylower in patients receiving triamcinolone immediately after surgery or one weekafter surgery than in patients without triamcinolone injection. In addition, therewas a significant difference between patients who received triamcinoloneintraoperatively and one week after surgery in terms of supratip skin thickness (P=0.027).
Conclusion:The results showed that triamcinolone injection is effective inreducing edema and supratip skin thickness. Also, triamcinolone injectionimmediately after surgery leads to better thinning of the supratip envelope.
Keywords: Rhinoplasty, Triamcinolone, Supratip, Skin thickness