Postoperative nausea and vomiting (PONV) is a common problem after surgery. Mastectomy is one of the high-risk operations to experience PONV, ranging from 21 to 92%. Preoperative carbohydrate drinks are offered as a solution to reduce PONV. Giving CHO is also an important component and it is recommended to achieve ERAS (enhanced recovery after surgery). CHO is associated with reduced catabolism and postoperative insulin resistance. This study aims to determine the effect of oral carbohydrate (CHO) drinks before surgery on the incidence of postoperative PONV mastectomy. The study used an experimental single-blind randomized test at Dr. HasanSadikin General Hospital (RSHS) Bandung. A total of 46 patients were divided into two groups, namely group K (control group, mineral water, n = 23 subjects) and group C (CHO group, n = 23 subjects). The results of the study were tested with Mann Whitney and results obtained in the period of 0-30 minutes, nausea and vomiting incidence in the control group was 57%, while the CHO group was only 22%. Whereas in 30-60 minutes, the incidence of nausea and vomiting in the control group was 91% and in the CHO group was 61%. At minutes 60-120, the incidence of nausea and vomiting in the control group was 78%, whereas the CHO group was only 61%. The results showed the CHO group has a reduced incidence of PONV in 0-120 minutes period post-mastectomy compared to the control group. The conclusion of the study is the administration of preoperative carbohydrate drinks can reduce the incidence of postoperative nausea and vomiting post-mastectomy compared with the control group.
Keywords: Mastectomy, Maltodextrin 12.5%, Preoperative carbohydrate, Post-operative nausea and vomiting, Enhanced recovery after surger
Abbreviations: Postoperative nausea and vomiting (PONV); Preoperative oral carbohydrate (CHO); Enhanced rcovery after surgery (ERAS); Dr. HasanSadikin General Hospital (RSHS)