Introduction: Peripheral arterial disease (PAD) is the Leading cause of amputation worldwide. The locations of the affected sector could have a certain predictive value Reading the evolution of these patients.

Objectives: Estímate the association between the frequency of major amputations and the topography of the PAD. Material and method: Observational, descriptive, analytical, retrospective study that estimates the association between the frequency of amputations and the aortoiliac or femoropopliteal topography of PAD, in patients with said diagnosis, hospitalized in the Arteriology service of the National Institute of Angiology and Vascular Surgery (INACV), during the years 2018 and 2019.

Results: In a sample of 220 stories, We found that high blood pressure (HBP) and smoking were the most frequent variables, affecting 71.8% and 60.5% of the sample respectively, 40.5% presented an aortoiliac pattern. , of these 55.1% were amputated and 59.5% were femoropopliteal, 58% of which were amputated, for a total of 125 amputations (56.8%). Supracondylar amputation was generally the most performed and infracondylar amputation was performed more frequently in patients with femoropopliteal topography. A more notable influence of smoking on the aortoiliac sector was evidenced. There was a similar probability of amputation for both sectors studied.

Conclusions: The type of occlusive pattern did not show an association with the frequency of amputations, nor the time in which it occurs, or with the associated risk factors.

Keywords: Peripheral Arterial Disease, Amputation and Occlusive Pattern