Statement of the problem: Breast cancer is the most common cancer in women worldwide.   Cancer is one of the most leading causes of death worldwide, and one of the biggest challenges in treating it is developing better ways to eradicate tumor cell growth.  Although various methods, such as surgery, chemotherapy, and radiation therapy, are used today to treat cancer, this disease mortality rate is still high due to the numerous shortcomings of each of these methods. Regenerative medicine field participates in cancer treatment and development of cancer models to improve the understanding of cancer biology. These methods are specific, safer, and more effective than conventional methods.  The purpose is highlighting the role of regenerative medicine in improving cancer treatment and promoting advanced future research in this field. 
Methodology: Application of several regenerative medicine approaches, including stem cell therapy, gene therapy, tissue engineering, and scaffolds.
Findings:  The implementation of regenerative medicine approaches in cancer treatment widens the hope avenue of treating severely treatable diseases. The course of treatment is shortened, and the need for repeated doses is eliminated. Scaffolds and tissue engineering constructions can be beneficial in the targeted delivery of antitumor drugs on tumor sites and overcome the short half-life of chemotherapy drugs. Scaffolds can facilitate conventional immunotherapies and the proper homing and distribution of immune cells in tumor sites by adjusting the tumor microenvironment. Also, they prevent the erosion of immune cells during the complex process of immunotherapy due to activating factors loaded on the scaffold. Altering the tumor microenvironment (TME) by laser-assisted treatment, radiation therapy, and Drug delivery leveraged nanomedicine's potential. These methods guide the tumors toward retraction direct or indirect effects on cancer cells and TME components.
Conclusion: It is hoped that the advancement of research in this field makes it possible to perform personalized cancer treatments.
Keywords: Cancer treatment, Regenerative medicine, Tissue engineering, Cell therapy, Stem cell, scaffold