This rearearch investigates Staphylococcus aureus pneumonia in mice by oral injection, Infection rate (65%) of histopathological testing reveals anumber of changes like the inflammaation that is expressed by polymorphonuclear leukocytes . This bacterium is typically responsible for a lung infection inflammatory reactions resulted from this infection may cause catching the infection of the lungs like increased neutrophilic inflammation and vascular leakage of serum protein into the lung This study suggests that staphylokinase production may be atypical virulence factor by means of Staphylococcus aureus that inhabit and lead to fibrinolysis and invasive infections

 

Keywords: Staphylokinase, Pneumonia, Staphylococcus aureus, Pathogenicity