In the history of mankind social, economical and ecological consequences of the Rinderpest has been severe. It has been often spread by trade and war. India had adopted scientific and ethical means to conquer Rinderpest without slaughter policy as being adopted in Europe. Focused quality vaccination audit on sero monitoring and clinical surveillance covering 480 million livestock population using 1642 million doses of vaccine from 1956-1998 was adopted. Food and Agriculture Organisation stated that Rinderpest eradication was instrumental in enabling the green revolution in India as it provided assured draft power for crop production before the induction of mechanized farming for crop production. Food and Agriculture Organisation estimated that India gained additional food production due to Rinderpest control program from 1965 to 1998 valuing 289 billion US Dollars. The cost benefit analysis indicated that for every dollar spent on Rinderpest control/eradication. The gains in term of additional milk, meat, animals, and draft power were at least 20 dollars. The cost of vaccination from 1955 to 2000 was nearly about US$33.36 billion. The impact of Rinderpest eradication on values (in million dollars) of milk and meat in India was substantial. Increase in milk production happened to be 4.796 times from the year 1995 to 2006 and increase in meat production 17.99 times from the year 1959 to 1995 and 18.69 times from 1995 to 2006. Increase in milk production was 72,719,000 tons from 1955 to 2006.Increase in term of milk production 26,71,000 tons from 1959 to 2006.In brief there has been 102.6 times increase in income from milk and 163.96 times in income from buffalo meat (1950-2006) the time when India totally gained freedom from Rinderpest as notified by Office of International Epizootics on 25 May 2006. Eradication of Rinderpest played a vital role to defeat hunger and poverty for improving livelihood of livestock keepers, especially in Africa and Asia.