Background: Pancreatic tuberculosis (TB) is very rare, mostly due to the antibacterial effects of the pancreatic enzymes. The association of thrombosisand tuberculosis has been reported but that of inferior vena cava (IVC) thrombosis and pancreatic tuberculosis is extremely rare and has only beenreported once.

Case presentation: A case of pancreatic Tuberculosis and IVCthrombosis presented with constitutional symptoms. Ultrasonography andcomputerized tomography showed a lesion in the head of the pancreas and alarge lymph mass. Magnetic resonance imaging (MRI) of (IVC) showed thrombosis in the IVC. Histological examination revealed necrotizing granulomasafter a laparotomy. The patient received antituberculosis chemotherapy and low molecular weight heparin.

Conclusion: Pancreatic TB is a challenge to diagnose especially in Resource-poor countries, which might lead to delay in treatment and worse complications.

Keywords: Pancreas, Tuberculosis, Thrombosis, Inferior vena cava, Case report