24th Global Immunology, Microbiology & Infectious Diseases Summit
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Accepted Abstracts

The Mixed Bacterial-Viral Intestinal Infections in Children of Early Age

Zemfira Mekhtiyevna Kuliyeva1, Lala Islakhovna Rustamova2*, Fatma Vagifovna Qilindjova1, Matanat Nabiyevna Mamedova4, Mehriban Musayevna Isayeva3 and Rena Mammadovna Akhundova3

1The Department of Pediatry, The Azerbaijan State Advanced Training Institute for Doctors Named After A.Aliyev, Baku, Azerbaijan
2The Department of Virulogy, The Scientific - Research Institute of Medical Prophylaxis NAMED after V.Y.Akhundov, Baku, Azerbaijan
3The Biolocical Faculti, “Odlar Yurdu” University, Baku, Azerbaijan
4The Department of Infectious Deseases, Azerbaijan Medical University, Baku, Azerbaijan

Citation: 
Kuliyeva ZM, Rustamova LI, Qilindjova FV, Mamedova MN, Isayeva MM et al (2021) The Mixed Bacterial-Viral Intestinal Infections in Children of Early Age. SciTech Immuno-Microbiology 2021.

Received: September 26, 2021         Accepted: September 28, 2021         Published: September 28, 2021

Abstract

The aim of investigation to study the of some clinico-microbiological characterisrics of mixed intestinal infections in children of early age.
Material and methods: the children under the age of 3 (infants and children), hospitalized in the Children’s Clinical Hospitals № 1 and 7 in Baku for the 2019 year have been examined. Bacteriological and serological studies were carried out to diagnose intestinal infections on the day of admission to hospital feces of sick children were take as material for analyses. Totally the 117 children have been observed. To convirm the diagnosis of bacterial intestinal infection feces were cultured with subsequent detection of sensitivity to antibiotics and for viral intestinal infection, immunochromatografic test was used. The bacteriological and serological investigations were arried out in the Scientific-Research Institute of Medical Prophylaxis named after V.Y.Akhundov during 2019 year.
Results: As a result of our studies, 33,3% (39) of children had mixed infection: a combination of viruses, particularly rotaviruses with St.aureus, E.Coli and C.albicans. From observing children 25 were under 6 month (21,4%), 15 – 7-12 month (12,8%), 77 – 1-3 years (65,8%). The combination of rotaviruses with other viruses (adenovirus and astrovrus) were the most frequently observed ones (5,1±2,0% and 6,8±2,3% accordingly) (p=0,167;p=0,067).Among opportunistic microbes the S.albicans was a leader. (In 18 (15,4%) patients). C.albicans was with rotavirus (p=0,063), in 5 (4,3±1,9%) with St.aureus and rotavirus (p=0,118) and in 4 (3,4±1,7%) with rotavirus and E.Coli (p=0,056). The viral intestinal infection with 2 associates occured in 5(4,3±1,9%) of patients – rotavirus + St.aureus + C.albicans and rotavirus + E.Coli + C.albicans (p=0,056). İt is possible that viral intestinal infection changes the susceptibility of the organism to a conditionally pathologic infection (opportunistic infection) and promotes the activation of endogenous infection.