Introduction:  In  any  community,  mother  and  children  constitute  a  priority  group. Antenatal care is given to promote, protect and maintain the health during pregnancy. Detection of “high risk” cases and their appropriate management forms an importance strategy in antenatal care. Pregnancy refers to the fertilization and development of one or more offspring known as a fetus or embryo in woman’s uterus. Pregnancy is an experience full  of  growth  change,  enrichment  and  challenge.  Pregnancy  is  a  normal process that results in a series of both physiological and psychological changes in a woman. Some of these are temporary changes that occur during pregnancy; others extend for a period of time after pregnancy; still others are permanent. The female body adapts to this change normally. Physiological changes of pregnancy occur gradually, but eventually affect all organ of system of woman’s body.

Design: A quantitative approach using pre experimental one group pre-test post-test design.

Participants: 60 Primigravida mothers were selected by using Non- Probability Convenient sampling technique in Mehsana District.

Interventions: Structured teaching programme was given to the primigravida mothers.

Tool: Self Structured Questionnaire was used to assess the level of Knowledge regarding Antenatal acre among Primigravida mothers

Results: In this study overall the highest percentage in the demographic data including the Age group 31% (31-40y), Educational status 63% (Secondary), Occupation 72% (House wife), Monthly income of family 55% (6000-9000rs), Type of family 64% (Joint family), No. Antenatal visit 55% (First), Gestational age 67% (1^st trimester), Source of information 55% (Health Personnel). The post- test mean score (11.33) was higher than the mean pre-test knowledge score (5.71). The calculated “T” value (15.23) was greater than the table value (2.00) at 0.05 level of significance. The Structured Teaching programme was effective in increasing the Knowledge regarding Antenatal care among Primigravida mothers. Chi-square test to associate with the level of knowledge and selected demographic variable. Conclusion: The findings of the study indicate that Structured Teaching Programme is effective in increase knowledge regarding Antenatal care among Primigravida Mothers.

Keywords: Assess effectiveness, Structured teaching programme, Knowledge