Objectives: Confirm existence of COVID-19 outbreak, conduct contact tracing, and recommend control measures.

Methods: Two COVID-19 cases in Sana'a Capital were met the WHO case definition. Data were collected from cases and contacts who were followed for 14 days. Nasopharyngeal swabs were taken for confirmation by Polymerase Chain Reaction (PCR).

Results: Two confirmed Yemeni male patients aged 20 and 40 years who had no travel history were admitted to hospital on 24 April 2020. Regarding the first patient, symptoms started on April 18th, 2020 then improved and discharged on May 5th while the second patient's symptoms started on April 22nd but died on April 29th, 2020. Both patients had 54 contacts, 17 (32%) were health workers (HWs). Four contacts (7%) were confirmed, two of them were HWs that needed hospitalization. The secondary attack rate (sAR) was 12% among HWs compared to 5% among other contacts.

Conclusions: First COVID-19 outbreak was confirmed among Yemeni citizens with high sAR among HWs. Strict infection control among HWs should be ensured. Physical distancing, maskwearing with appropriate disinfecting measures should be promoted especially among contacts. There is a need to strengthen national capacities to assess, detect, and respond to public health emergencies.

Keywords: COVID-19, Contact tracing, Health workers, Outbreak, Yemen