Artificial intelligence (AI) and machine learning (ML) algorithms have transformed various industries, including healthcare. Healthcare organizations are now using AI and MLalgorithms to drive strategic leadership and decision-making, as they provide insights that help organizations manage resources, improve patient outcomes, and increase efficiency. This abstract examines how AI and ML algorithms are used in healthcare to drivestrategic leadership. The paper also explores the benefits and challenges associated with using these technologies in healthcare. The study found that AI and ML algorithms can help healthcare organizations make data-driven decisions, optimize resource allocation, and improve patient outcomes. However, there are still challenges related to data quality and privacy that must be addressed to ensure that AI and ML algorithms are used effectively in healthcare.