Global Congress on Infectious Diseases & HIV/AIDS
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Accepted Abstracts

Digeorge Syndrome and Immune Thrombocytopenia Purpura

Amna Mohsin1*, Mahasin Shaheen2
1 Lister hospital East and North Hertfordshire NHS trust, UK
2 Al Qassimi Hospital, UAE

Citation: Mohsin A, Shaheen M (2020) Digeorge Syndrome and Immune Thrombocytopenia Purpura. SciTech Infectious Diseases 2020. Mauritius 

Received: February 11, 2020         Accepted: February 19, 2020         Published: February 20, 2020

Abstract

Digeorge Syndrome (22q11.2 deletion syndrome) comprises of various congenital anomalies such as cardiac defects, specific facial appearances, defective T cell production, hypocalcemia etc. This syndrome is also associated with various autoimmune diseases. Here we present a case report which shows association of Immune thrombocytopenia purpura with Digeorge Syndrome. A 15 years old boy born with congenital cardiac defects, diagnosed as 22q11.2 deletion syndrome, underwent corrective cardiac surgeries after birth. He developed thrombocytopenia at this age, requiring admission and platelet transfusions. His further work up confirmed Immune thrombocyte penic purpura and its presentation being related to the genetic disorder itself.
Keywords: Cleft Palate,  Congenital Cardiac Anomalies, 22q11.2 Deletion, Digeorge Syndrome, Immune Thrombocytopenic Purpura, Purpuric Rash