Background: Liver disorders comprise 3% of all pregnancy complications. All liver disorders, pregnancy specific, pregnancy related and pregnancy unrelated disorders have both maternal and fetal effects. The present study was conducted to study the effect of liver disorders in pregnancy..
Objective: To study the effect of liver disorders on pregnancy outcome.
Study-Design: cohort study
Methods: All pregnant patients with clinical and biochemical evidence of liver dysfunction were taken as cases. Pregnant women with normal liver function tests were taken as controls. All patients were followed during pregnancy and postpartum. Maternal and fetal outcome was studied
Results: A total of 140 patients were included- 70 cases and 70controls. Maternal and fetal outcome was studied in both the groups..PPH and oligohydroamnios were most frequent among cases with p value of 0.034 and 0.035 respectively.Similarly preterm birth,RDS and perinatal asphyxia was more common in cases with a p value of 0.011,0.001 and 0.005 respectively
Conclusions: Study concludes that liver disorders in pregnancy have adverse maternal and fetal complications.