Post-Quinine Bilious Hemoglobin Fever in an 8-Year-Old Child Monitored for Severe Malaria at the Yalosase Health Center, Isangi, DR Congo
Dieudonne Lobela Bumba1,2,3*, Issa Yakusu Issa4, Bruce Wembolua Shinga5, Muyobela Kampunzu6, Gilbert Bokungu Isongibi1, Francy Baelongandi Folo7, Jacques Ossinga Bassandja4
1Higher Institute of Medical Techniques of Yangambi, Yangambi, Democratic Republic of Congo
2Yalosase Health Center, Rural Health Zone of Isangi, Isangi, Democratic Republic of Congo
3Lomboto Reference Health Center, Isangi Rural Health Zone, Isangi, Democratic Republic of Congo
4Department of Internal Medicine, Faculty of Medicine and Pharmacy, University of Kisangani, Kisangani, Democratic Republic of Congo
5Infectious and Tropical Diseases Department, National University Hospital of Fann, Dakar, Senegal
6Department of Pediatrics, Faculty of Medicine and Pharmacy, University of Kisangani, Kisangani, Democratic Republic of Congo
7Provincial Health Division, Tshopo, Democratic Republic of Congo
Citation: Bumba DL, Issa IY, Shinga BW, Kampunzu M, Isongibi GB et al (2021) Post-Quinine Bilious Hemoglobin Fever in an 8-Year-Old Child Monitored for Severe Malaria at the Yalosase Health Center, Isangi, DR Congo. SciTech Immuno-Microbiology 2021.
Received: July 22, 2021 Accepted: July 24, 2021 Published: July 24, 2021
It has been known since March 2013 that Artesunate is considered the gold standard treatment for severe malaria. However, in our regions, the drug of choice available to treat patients with severe malaria remains quinine until today. However, frequent and sequential use of quinine is associated with the occurrence of hemoglobinuria. We report a probable case of bilious hemoglobin fever (BHF) in an 8-year-old child. This was an 8-year-old child with a history of frequent and recent treatment with quinine, received in consultation for coca-cola urine emission with rapid diagnostic test (RDT) positive. In search of a particular terrain, the retroviral and syphilitic serologies were negative. Considering the context, the diagnosis of post-quinine hemoglobin bilious fever (BHF) was retained and the patient had progressed well after administration of artemisinin and its derivatives. The child was followed, on an outpatient basis, without any sequelae. It would therefore be prudent for the time being to avoid them in prophylaxis and self-medication.
Keywords: Bilious hemoglobin fever, Severe Malaria, Quinine, Isangi
Abbreviations: BHF- Bilious Hemoglobin Fever, RDT- Rapid Diagnostic Test