26th International Conference on Psychiatry, Neuro and Mental Health
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Accepted Abstracts

Anti-NMDA Receptor Encephalitis Presenting as an Acute Psychotic Episode

Philip Kumar Boyanapally*, Kamelendranath Choudary Pamulapati 
Chetana Hospital, India

Citation: Boyanapally PK, Pamulapati KC (2021) Anti-NMDA Receptor Encephalitis Presenting as an Acute Psychotic Episode. SciTech Mental Health 2021. 

Received: July 22, 2021         Accepted: July 24, 2021         Published: July 24, 2021


Anti-NMDA receptor (NMDAR) encephalitis is an autoimmune disorder with prominent psychiatric symptoms. Patients usually present with acute behavioural change, psychosis, catatonic symptoms, memory deficits, seizures, dyskinesia, and autonomic instability.
We describe a 28 yrs old female patient who had previous 2 brief episodes of psychosis and has now again presented with psychosis but then clinical condition gradually worsened and she developed dyskinesia, catatonic symptoms and seizures. Though her routine blood work, brain imaging was normal, a confirmative diagnosis of NMDAR encephalitis was made by positive CSF studies. Patient was treated with methylprednisolone and plasmapheresis to which she showed response. This case illustrates the importance of considering NMDA R encephalitis as a differential diagnosis especially in young female with neuropsychiatric symptoms and progressive disturbance of consciousness, and associated involuntary movements, since prognosis depends on early recognition and treatment.