Objective: Antiretroviral therapy is an effective technique for controlling virus spread and extending the lives of those who are infected. The focus of the research was to look at the link with compliance and counseling in HIV-infected people at the Korle Bu Teaching Hospital in Accra, Ghana.

Methods: A cross-sectional study was undertaken on 103 HIV-infected people who had been taking ART for more than 6 months at the hospital. The study employed a basic random sampling approach, which provided each participant with an equal opportunity to participate. Statistical Packages for Social Science (SPSS) version 22 was used to evaluate the quantitative data. Descriptive statistics such as frequencies and percentages were used to characterize patients' social-demographic characteristics. To explore about a linkage with adherence and counseling, correlation was used.

Results: Data of the study was analyzed with SPSS using correlation. Based on the results, the study discovered a substantial linear link between counseling and antiretroviral medication adherence, with a Pearson r correlation of .318 and a significant linear of.001.

Conclusion: This implies that a counseling session might aid in the understanding of facts provided regarding the infection and medicine, as well as in adhering to the regimen prescribed. In addition, aids in the minimization of the fear of stigmatization.