Background: The ongoing COVID-19 pandemic has proved to be a public health challenge of immense proportion and has challenged the existing health system and supply chains in India. The State of Odisha was among the first to set up dedicated COVID-19 hospitals. Kalinga Institute of Medical Sciences (KIMS), Bhubaneswar is one of the first institutes to have a COVID hospital in the State. The study was aimed to determine the clinical profile, radiological presentations, laboratory findings and clinical outcome of patients infected with the novel SARS CoV-2 virus receiving treatment at KIMS, Odisha.
Materials and Methods: A retrospective analysis of the clinical and laboratory data for patients admitted with COVID-19 diagnosis at the dedicated COVID-19 hospital during the period 5th April 2020 to 4th June 2020 was done.
Results: A total of 272 consecutive COVID-19 cases were included in this study. Majority of the patients were males (83∙57%). Most of the patients (79∙04%) were asymptomatic. Mortality was 1∙9%. Among the symptomatic cases, fever (18∙38%), cough (17∙27%), dyspnea (16∙91%) and myalgia (14∙7%) were encountered. Mild severity was noticed in 78∙94% cases. In 13% cases, there was a delayed viral clearance. Presence of co-morbidities did not seem to affect the outcomes. Typical features of novel SARS CoV-2 infection on CT images of thorax were seen in 12∙13% cases. Raised CRP was witnessed as biomarker of inflammation. Out of the 5 deaths encountered, 2 patients had diabetes mellitus, 2 were hypertensive and one COPD respectively.
Conclusion: COVID-19 may have a delayed viral clearance beyond two weeks. Discordance between CT images and the clinical condition may also be observed. Diabetes, hypertension and high blood CRP levels do not appear to have a significant effect on the outcome as per our study.
Keywords: COVID-19, SARS CoV-2, Clinical profile, Radiological findings, Comorbidities, Fatality