Global Conference on Nanomedicine, Nanobiology, Nanotechnology & Pharmacology
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Accepted Abstracts

Antibacterial effect of bio and chemosynthesis silver nanoparticles on biofilm forming Pseudomonas oryzihabitance

Shaimaa Obaid Hasson*
Al-Qasim Green University, Iraq

Citation: Hasson SO (2019) Antibacterial effect of bio and chemosynthesis silver nanoparticles on biofilm forming Pseudomonas oryzihabitance (2019) SciTech Nanosciences-Pharma 2019. Tokyo: Japan

Received: March 09, 2019         Accepted: May 05, 2019         Published: May 08, 2019

Abstract

Silver nanoparticles was considered a powerful antimicrobial agents recently especially, after increasing incidence of diseases associated with biofilm and multi-drug resistant pathogens which necessary required to find a novel path to eradicate that’s challenge. The present study aims to biosynthesize silver nanoparticles (SNPs) using a cell-free extract of Enterobacter cloacae and chemosynthesis by NaBH4 (Sodium borohydride) as reduction agent and evaluate their antibacterial activity on biofilm forming Pseudomonas oryzihabitance and in combination with imipenem antibiotics. Antimicrobial effect of silver nanoparticles in both types and in combination with imipenem were evaluated by agar well diffusion. The results revealed that’s a good response of biofilm Pseudomonas oryzihabitance toward silver nanoparticles in both types and in combination with imipenem, the antimicrobial effect was increased and enhanced. From this study, the biological and chemical silver nanoparticles were considered a novel and decisive solution against biofilm and multidrug-resistant bacteria with a preference of biological silver nanoparticles as well as in combination with imipenem.
Keywords: Biological    silver nanoparticles, chemical silver nanoparticles, biofilm, Pseudomonas oryzihabitance, imipenem